TY - JOUR TI - Simulation Optimization for the Stochastic Economic Lot Scheduling Problem with Sequence-Dependent Setup Times AB - We consider the stochastic economic lot scheduling problem (SELSP) with lost sales and random demand, where switching between products is subject to sequence-dependent setup times. We propose a solution based on simulation optimization using an iterative two-step procedure which combines global policy search with local search heuristics for the traveling salesman sequencing subproblem. To optimize the production cycle, we compare two criteria: minimizing total setup times and evenly distributing setups to obtain a more regular production cycle. Based on a numerical study, we find that a policy with a balanced production cycle outperforms other policies with unbalanced cycles. DO - http://dx.doi.org/10.1016/j.ijpe.2014.05.006 SP - 170 EP - 176 UR - http://www.sciencedirect.com/science/article/pii/S0925527314001625 PY - 2014-01-01 JO - International Journal of Production Economics AU - Löhndorf, Nils AU - Riel, Manuel AU - Minner, Stefan ER -